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Volume 2
DEMENTIA AND DEMENTIA CARE
ADVANCES IN ADDICTION SCIENCE AND MEDICINE
July 24-25, 2019 | Rome, Italy
10
th
International Conference on
2
nd
World Congress on
&
Addiction Science 2019 & Dementia Care 2019
July 24-25, 2019
Journal of Clinical Psychiatry and Neuroscience
Validation of a short telephone test (COGTEL) for the diagnosis of symptomatic
Alzheimer's disease (AD)
Maria Skondra
University of Patras, Greece
T
he identification of cognitive impairment in general practice requires short but accurate tests. For epidemiologic surveys
and genetic family studies cognitive tests are desirable which can be administered over the telephone. We assessed the
ability of the Greek version of the Cognitive Telephone Screening Instrument (COGTEL) to identify patients with symptomatic
Alzheimer's disease (AD) and compared it with the diagnostic accuracy of the conventional modified Mini Mental State
Examination (3MS). The study refers to 15 patients of the outpatient clinic for cognitive disorders of the University Hospital of
Patras who suffered from symptomatic Alzheimer’s disease (ten with mild dementia and five with mild cognitive impairment).
The study also included 17 cognitively unimpaired age-matched individuals. The COGTEL and 3MS were validated against an
expert diagnosis based on a comprehensive diagnostic workup which included the Montreal Cognitive Assessment (MoCA).
Statistical analysis was performed using the Receiver-Operator-Characteristics (ROC) method. The COGTEL outperformed the
3MS in the distinction between symptomatic AD and cognitively unimpaired individuals (Area under the curve, AUC: 0.92 vs.
0.89, respectively). The COGTEL is a short and practical but accurate telephone test for the identification of symptomatic AD for
use in epidemiological surveys and genetic family studies. The interview achieves higher diagnostic precision than the 3MS and
contributes to a valid assessment of cognitive performance.
Biography
Maria Skondra is a PhD candidate of the Medical Faculty of Medicine (University of Patras) and graduate of the Department of
Nursing (Western Greece University of Applied Sciences). Her scientific activity is focused on early diagnosis of cognitive impairment in
neurodegenerative neurocognitive disorders. She is a graduate of the Hellenic Red Cross Nursing School as well as of the Department
of Sociology (Panteion University of Athens). She completed postgraduate studies at the Department of Social and Educational Policy
of the University of Peloponnese with specialization in the field of "Health Institutions and Policies". She has been working as a nurse
in the Greek Red Cross since 2001 and as scientific scholar of the Department of Nursing (Western Greece University of Applied
Sciences) since 2016.
mskon@hotmail.grJ Clin Psychiatr Neurosci, Volume 2