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Volume 3
Journal of Neurology and Clinical Neuroscience
Neurosurgery 2019 & Neuroimmunology 2019
May 22-23, 2019
Neurosurgery and Neurological Surgeons
Neuroscience and Neuroimmunology
May 22-23, 2019 London, UK
6
th
Annual Meeting on
9
th
Global Summit on
&
J Neurol Clin Neurosci, Volume 3
Prevalence of inherited/congenital neurological disorders inAzad Jammu and Kashmir
Sadia Idrees
1
, Zeeshan Anjum
1
, Naheed Bashir Awan
1
, Syeda Ain-ul-Btool
1
, Farhat Rafique Kiani
1
, Qudir Javed
1
, Mohsan Hanif
1
Fauzia Saeed
2
and
Ghazanfar Ali
1
,
1
Department of Biotechnology, University of Azad Jammu and Kashmir, Muzaffarabad, Pakistan
2
Department of Zoology, University of Azad Jammu and Kashmir, Muzaffarabad, Pakistan
Statement of the Problem:
Large scale epidemiological studies on inherited/congenital neurological diseases are rare in Pakistan
and also in Azad Jammu and Kashmir. Therefore, we conducted a population based cross sectional epidemiological study on
a stratified randomly selected samples from the four major districts of AJ &K to study the four major inherited/ congenital
neurological disorders which includes; intellectual disability, microcephaly, neuromuscular dystrophy and Parkinson’s disease.
Methodology:
Families with inherited/congenital neurological disorders were randomly recruited through door to door survey.
Approval for this study was obtained by board of advanced studies from University of Azad Jammu and Kashmir.
Findings:
Total 10,000 individuals were selected for interview among which 9711 (97.11%) took part in the study while 289(2.89%)
refuse to take part in this study. Among responsive, the total number of affected individuals with different neurological disorders
was 466 (4.80%) with an age range of 1-60 years. According to this data prevalence of neurological disorders in males was more
272 (5.67%) than the females 194(3.94%). The highest prevalence was recorded in age <18 years 253 (6.40%). Among the total
positive cases intellectual disability was most frequent 337 (72.31%), followed by microcephaly 64 (13.7%), neuromuscular
dystrophy 51(10.90%) and Parkinson 14 (3. 00%).
Conclusion & Significance:
Present data suggests that inherited intellectual disability is the most frequent among all neurological
disorders so further exploration, population base studies and genetic counseling is necessary.
sadiamughal611@gmail.com