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Volume 3
Journal of Reproductive Biology and Endocrinology
WCGO2019
May 13-14 , 2019
Gynecology and Obstetrics
May 13-14 , 2019 Tokyo, Japan
2
nd
World Congress on
Incidental intravascular leiyomyomatosis: A case report and review of the literature
Samara Tahreen Sabur
Northern Beaches Hospital, Australia
Intravascular Leiyomyomatosis (IVL) is a rare smooth muscle cell tumour that is histologically benign with
metastatic behaviour. The tumour arises from the uterus and grows within the venous system, extending to
the inferior vena cava, right-sided cardiac chambers and pulmonary vessels. IVL can be fatal, resulting in
thromboembolic events, congestive heart failure and intra-pulmonary leiyomyomatosis. There is also a risk of
recurrence if the tumour is not completely resected.
Presentation usually occurs after the disease has advanced with symptoms of haemodynamic instability,
dyspnoea, palpitations, chest or abdominal pain.2 Typically, diagnosis is based on macroscopic description of
worm-like tumour projections in the veins and/or microscopic evidence of intraluminal leiyomyomas.
We report a case of a 44-year-old woman who underwent a total abdominal hysterectomy and bilateral
salpingectomy for simple hyperplasia, diagnosed from uterine curettage performed for menorrhagia.
Intraoperatively, increased vascularity and aberrant vessels were noted on the serosal surface. The macroscopic
pathology examination was normal, however, the histopathology demonstrated smooth muscle tumours in 2
vessels, consistent with IVL.
The patient underwent computed tomography imaging of the chest and abdomen to rule out metastases and is
scheduled for yearly follow-up due to the risk of recurrence. This case highlights a rare but important diagnosis
that gynecologists should be suspicious of when abnormal vascularity is seen on the uterus, especially due to
the high risk of morbidity and recurrence with IVL. We review the literature and discuss management options
for optimal outcomes of this disease.
Biography
Samara Sabur is a junior medical doctor, training in obstetrics and gynecology at the Northern Beaches Hospital in Sydney, Australia.
She is currently completing a Master of Public Health through the University of Sydney and is an associate lecturer at the School
of Medicine in University of Western Sydney. She has previously presented research at the European Congress of Obstetrics and
Gynecology as well as the Australasian Gynecological and Endoscopy Society annual scientific meeting.
samara.sabur@gmail.comJ Reprod Biol Endocrinol, Volume 3