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Volume 3
Current Research: Integrative Medicine
Chronic Diseases 2018
July 16-17, 2018
Chronic Diseases
July 16-17, 2018 Berlin, Germany
2
nd
International Conference on
Curr Res Integr Med 2018, Volume 3
DOI: 10.4172/2529-797X-C1-003
A functional study to relate the prevalence of
H
.
pylori
infection to starch rich diet on the island of St.
Vincent and the Grenadines
Daphne Santhosh, Melissa Brown, Taslima Jaby and Maurissa Harris
Saint James School of Medicine, Caribbean
H
elicobacter pylori
is an important risk factor for gastritis and gastric carcinoma. It is a Gram-negative, flagellated, motile
bacterium that adapts well to the acidic gastric environment by elucidating the enzyme urease which neutralizes the gastric pH,
allowing the bacterium to adhere to the gastric mucosa causing infection and inflammation leading to peptic ulcers. However, other
important factors are thought to be responsible, such as diet, and familial genetic predisposition. A study by Mard et al. in 2014 showed
adequate nutritional status, especially high consumption of fruits, vegetables, and vitamins appear to protect against the pathological
consequences of
H. pylori
infection. The aim of our study was to evaluate the association of dietary consumption of starch rich diet
common to the island of St. Vincent and the Grenadines to
H. pylori
. This was a cross-sectional study conducted between January and
March of 2017. Dietary consumption of participants was assessed using food frequency questionnaire approved by the institutional
research committee (IRC) of St. James School of Medicine along with informed/ signed consent from 200 willing participants.
H.
pylori
infection status was diagnosed using the one-step
H. pylori
blood test kit. Among a sample size of 200 (n=200); 14.5% were
positive for
H. pylori
infection while 85.5% were negative. The data among the 14.5% were statistically insignificant between the sexes
(males=16%) and (females=13%) (p>0.05). Among the eight variables, family history and incidence of
H. pylori
was in accordance
with established data with 33% showing positive with family history vs. 13% without; with a statistically significant data (p=0.031).
A higher trend was noticed for complex carbohydrate consumption in
H. pylori
infected individuals but the data was statistically
insignificant (p=0.63); but a larger sample size would have benefited the research towards the hypothesis. Among the food groups; starch,
protein and vegetables were of higher consumption than other food groups but the data was statistically insignificant (p=0.61).
dsanthosh@mail.sjsm.org