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Joint Event
November 29-30, 2019 | Frankfurt, Germany
28
th
International Conference on
3
rd
International Conference on
Diabetes and Endocrinology
Diabetes and Metabolism
&
2
0
1
9
CONGRESS
DIABETES
2019
DIABETES
Journal of Endocrine Disorders & Surgery | Volume 3
The Impact of Oral Multivitamin Supplementation on Oxidative Stress and Lipid Profile
among Sudanese Patients with T2DM
Abd Elgadir A Altoum
Gulf Medical University, UAE
Aim:
The objective of the current study was to assess the
influence of oral multivitamins supplementation on some
oxidative stress parameters (serum Vitamin A, C, E, Zinc,
Malondialdehyde (MDA)) and lipid profile among Sudanese
patients with type- 2 diabetes mellitus (T2DM).
Material And Method:
Three hundred Sudanese patients
with T2DM and Hundred healthy subjects (control group)
were enrolled in this cross-sectional study. Blood was
collected after overnight fasting for 10-12 hrs. Fasting plasma
glucose (FBG), lipid profiles, Glycosylated haemoglobin
(HbA1c%), Serum zinc, Malondialdehyde (MDA), Vitamins A,
E, and C levels were measured using standardised laboratory
techniques. Data was collected with the help of a structured
questionnaire and direct interview.
Results:
Biochemical parameters of the study population
were shown a highly significant difference (P value < 0.05),
between the means of serum vitamin A, C, E, Zinc, MDA,
HbA1c, triglycerides, HDL, FBG, total cholesterol and LDL.
Significant differences in serum vitamin A, C, E, Zinc, MDA,
triglycerides, HDL and FBG between people with diabetes
who used multivitamins and diabetics who did not use it
(P-value < 0.05).
Conclusion:
The study observed a significant increase in
serum levels of vitamin A, C & E and other biomarkers
parametersinpatientswithT2DMwhotakeoralmultivitamins
supplements; such improvement may lead to minimising the
diabetic complications. Further studies are needed to explore
the possible therapeutic role of multivitamins supplements
for T2DM patients.
Speaker Biography
Abdelgadir Elamin is an Assistant Professor in Medical Laboratory
Sciences Program of College of Health Sciences, Gulf Medical University.
He has more than 15 years of teaching and research experience and
published several scientific papers in reputed journals. Education
B.Sc.Medical Laboratory Sciences (Clinical Chemistry) from University of
Science and Technology, Sudan in 2002.
M.Sc.Clinical Chemistry from
Sudan University for Sciences and Technology, Sudan in 2008. Ph.D. in
Clinical Chemistry from University of Science and Technology, Sudan in
2015. Research Interests focus on Oxidative stress-induced risk factors
associated with the metabolic syndrome Diabetes Cardiovascular
Disorders and Antioxidant.
e:
Dr.abdel@gmu.ac.ae