nephrology-chronic-diseases-2019-posters-abstracts

Page 24

Volume 2

Journal of Clinical Diagnosis and Treatment

Annual Nephrology & Chronic Diseases 2019

May 20-21, 2019

Nephrology

Chronic Diseases

May 20-21, 2019 London, UK

Annual Conference on

International Conference on

Notes:

Physical and mental fitness in hemodialysis patients: A systematic review

Sapna Chandgadkar, H G Virani

and

Amol Mahaldar

Goa Engineering College, India

eople with End Stage Kidney Disease (ESKD) on Hemodialysis (HD) experience multiple catabolic

processes, including loss of albumin and amino acids during dialysis, metabolic derangements, and

changes in skeletal muscle associated with conditions of muscle disuse. These changes result in muscle atrophy

(loss of lean muscle mass). The presence of neurogenic (muscle atrophy or loss associated with nerve disorder),

myogenic (damage intrinsic to the muscle), and mixed (neurogenic and myogenic) changes intrinsic to the

skeletal muscle in people with ESKD on HD may further compromise the integrity of the motor-unit complex

and contribute to muscle atrophy. The paper is a systematic review of the interventions to improve fitness

levels of patients on maintenance HD. The results of the meta-analysis indicate the following: The survival

of patients on maintenance haemodialysis is increased by improving their physical performance. Chronic

Dyspnoea is one of the most common symptoms of patients on haemodialysis and is intractable to therapy

due to its multifactorial origin. Dyspnoea is due to systemic inflammation and is caused by a combination of –

anaemia, malnutrition and muscle wasting. The 6-minute walk test can be used to classify patients into various

fitness levels as an OPD procedure and help patients get an objective evaluation of their fitness.

Biography

Sapna Chandgadkar is a master’s Student at Goa Engineering College. She is working with Dr Virani, HOD, Electronics Engineering

and Dr Mahaldar, HOD, Nephrology, Manipal Hospital. Their research focuses on improving the quality of life of patient on hemodialysis,

in emerging markets. The objective is to develop a Markov Model of the interventions that could help patients on Hemodialysis to

improve their fitness levels a step at a time.

Sapna Chandgadkar et al., J Clinical Diagnosis and Treatment, Volume 2