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Volume 2 Journal of Clinical Diagnosis and Treatment Annual Nephrology & Chronic Diseases 2019
May 20-21, 2019
Nephrology
Chronic Diseases May 20-21, 2019 London, UK
19th Annual Conference on
3rd International Conference on
&
Chronic fatigue syndrome: A unifying hypothesis for an etiological diagnosis
Kaiss Jarkass
Ministry of Education, Syrian Arab Republic
Statement of the Problem: ME/CFS is a disabling complex chronic illness affecting millions of people around
the world. It has a devastating impact on the lives of patients and their families, causing losses estimated at
billions of dollars annually in medical bills and lost incomes. The present paper seeks to put forth a plausible
unifying hypothesis for an etiological diagnosis of this debilitating illness. It begins with a summary of
hypotheses that have been suggested for explaining ME/CFS. An attempt is then made to put together various
pathogenetical and pathophysiological mechanisms into one hypothesis, suggesting a single etiological factor
and linking all other mechanisms to one causality. Firstly, the paper defines several criteria that any diagnosis
should meet in order to be considered plausible. Secondly, it suggests a clinical diagnosis that might meet
the criteria and account for the constellation of symptoms associated with ME/CFS. It explains the plethora
of pathophysiological mechanisms and manifestations in the light of the suggested diagnosis. Thirdly, it
anticipates and attempts to answer some of the issues that may be raised. Fourthly, it pinpoints challenges that
need to be addresses in the light of the suggested causality. Finally, the paper suggests a plan for diagnosing
patients with ME/CFS and a plan for ex juvantibus treatment defining challenges and strategies for further
study.
Biography
Kaiss Jarkass graduated from Saint Petersburg State Medical University I.P. Pavlov (Formerly, First Leningrad I. P. Pavlov Medical
Institute) in 1988. He has 20 years’ experience in field work both in government sector, as a school health physician, and in private
practice as a GP. He has interest mainly in infectious diseases, chronic illnesses and ME/CFS.
Kaiss Jarkass, J Clinical Diagnosis and Treatment, Volume 2