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Page 40
Volume 3
Current Research: Integrative Medicine
Nursing Care & ICNND 2018
October 22-23, 2018
October 22-23, 2018 Madrid, Spain
46
th
World Congress on
Nursing Care, Neurology and Neuromuscular Diseases
Necrotizing enterocolitis in a preterm infant newborn and role of feeding, an update: A clinical case report
Amr I M Hawal
1
and Khaled M
2
1
Prime Medical Center, UAE
2
Latifa Hospital-DHA, UAE
I
t is a clinical case presentation of a male preterm infant newborn (+31 weeks) who was delivered in our hospital and transferred
to our NICU because of prematurity, Very Low Birth Weight (VLBW) and need to respiratory support. Baby shortly undergo
Necrotizing Enterocolitis (NEC) on 5
th
day of life shortly after start of expressed milk feeding, which was early detected by use
of Near Infrared Abdominal Spectroscopy (NIRS). Baby was deteriorated clinically in a couple of hours and undergone intestinal
perforation with peritonitis, so, abdominal exploration surgery with intestinal resection and end to end anastomosis was done
urgently. Baby improved gradually and early feedings was started and gradually increased up to full feedings with use of Human
Fortified Milk (HMF), probiotics and prebiotics. The study stated the evidence-based feeding strategies guidelines for necrotizing
enterocolitis among very low birth weight infants and role of trophic feedings, probiotics, prebiotics and micronutrients in prophylaxis,
prevention and management of NEC. Prematurity is the single greatest risk factor for NEC and avoidance of premature birth is the
best way to prevent NEC. The role of feeding in the pathogenesis of NEC is uncertain, but it seems prudent to use breast milk (when
available) and advance feedings slowly and cautiously. NEC is one of the leading causes of mortality and the most common reason
for emergent GI surgery in newborns. NEC remains a major unsolved medical challenge, for which no specific therapy exists and
its pathogenesis remains controversial. A better understanding of the pathophysiology will offer new and innovative therapeutic
approaches and future studies should be focused on the roles of the epithelial barrier, innate immunity and microbiota in this disorder.
Bioinformatics modeling is a new emerging strategy aimed at understanding the dynamics of various inflammatory markers and their
application in early diagnosis and treatment.
amr106@gmail.comJ Current Res: Int Medicine 2018, Volume 3
DOI: 10.4172/2529-797X-C2-006