pediatrics-neonatal-healthcare-2017-posters-abstracts

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Pediatrics & Neonatal Healthcare 2017
September 11-12, 2017 Los Angeles, CA, USA
14th World Pediatrics &
Neonatal Healthcare Conference
Journal of Pediatric Health Care and Medicine Volume 1, Issue 1
Notes:
Risk stratification models to predict adverse neonatal outcome: Additive value of
standard electrocardiography
Fabio Angeli
Hospital Santa Maria della Misericordia, Italy
Hypertension disorders complicate approximately 6%–11% of all pregnancies and remain leading causes
of poor outcome, including placental abruption, organ failure, cerebrovascular accident and disseminated
intravascular coagulation. These disorders are also associated with increased fetal risk of intrauterine growth
restriction, intrauterine death and prematurity. Epidemiological evidences supporting the worse prognosis
associated with hypertension in pregnancy provide a strong basis for developing perinatal morbidity and mortality
risk prediction models. Of the many risk markers for hypertensive disorders, some are known at booking and
increase the risk of hypertensive disorders two- to fourfold. They include pre-existing hypertension, diabetes
mellitus and renal disease, previous preeclampsia, antiphospholipid antibody syndrome, overweight/obesity,
inter-pregnancy interval ≥10 years, and multiple pregnancy. Recently, the additive value of some instrumental
techniques (including uterine artery Doppler velocimetry, electrocardiography [ECG] and ambulatory BP
monitoring) and their combinations with maternal factors and biochemical markers to refine risk stratification
for hypertensive disorders in pregnancy has also been evaluated. In this context, some observations suggested
that abnormal ECG patterns may increase the risk for hypertensive disorders of pregnancy. Specifically, available
data support the concept that specific ECG patterns occurring in the first trimester of pregnancy may have clinical
relevance for the risk prediction of maternal and neonatal complications. Left atrial abnormality in lead V1
has been suggested as an independent predictor of hypertensive disorders and other pregnancy complications
including fetal growth restriction, HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome,
placental abruption, stillbirth, premature delivery and neonatal death.