pediatrics-neonatal-healthcare-2017-posters-abstracts

Page 41

Pediatrics & Neonatal Healthcare 2017

http://pediatrics.cmesociety.com

September 11-12, 2017 Los Angeles, CA, USA

World Pediatrics &

Neonatal Healthcare Conference

Journal of Pediatric Health Care and Medicine Volume 1, Issue 1

Notes:

Effect of maternal hypertensive disease on the outcome of low birth weight infants

Ahsan Akhtar, Menogh Glen Valentine, Patrick Leblanc

and

Pramod Shrestha

The Brooklyn Hospital Center, USA

ypertension (HTN) disorders are the most common medical complication occurring in 12-22% of all

pregnancies. Preeclampsia is responsible for about 15.9% of maternal deaths in USA. We hypothesized that

early onset pre-eclampsia has greater impact on morbidity and mortality. Electronic medical records from January

2014 to December 2015 of infants birth weight (BW)<1500g were reviewed. Patients with co-morbidities were

excluded. We identified 20 cases with HTN and preeclampsia, 69 healthy controls. The demographics, mode

of ventilation, length of stay (LOS), morbidity and mortality were analyzed with Chi-square test. The Mann

Whitney test was used to analyze the duration on different modes of ventilation. A p-value <0.05 was considered

statistically significant. No difference was noted in the maternal demographic data or laboratory values. No

significant difference was noted in mode and duration of respiratory support, mortality rates, LOS, vasoactive

support, blood products, retinopathy and brain abnormalities. The results were stratified to compare BW<1000

g and 1000-1499 g and continued to show no statistical difference in any of the measured outcomes. Comparing

cases with BW<1000 g vs. 1000-1499 g, the mode and duration of respiratory support was significantly longer

in <1000 g. LOS, vasoactive support, blood products and brain abnormalities were all higher in the <1000 g

group. Comparing the controls with BW<1000 g vs. 1000-1499 g, LOS and mortality rate were higher in the

<1000 g group. No differences were noted in vasoactive support, blood products and brain abnormalities. We

found no significant difference in adverse outcomes between the groups. Even after further sub-categorizing the

subjects based on BW, there still was no statistical difference between the groups. Infants born at a lower BW are

believed to have more adverse outcomes after birth. Very low BW has a greater chance of morbidity and mortality

compared to low BW infants if born to mother with hypertension.