cam-therapies-2017-posters-accepted-abstracts

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Current Research: Integrative Medicine

CAM Therapies 2017

September 18-19, 2017 Charlotte, USA

International Meeting on

Complementary and Alternative Medicine & Therapies

Comparison of anxiolytic effects of the homeopathic complex vita-C 15 in comparison

with

Aconitum napellus

in the acutely stressed C57BL6 mice

Charis Liew Siaw

Cyberjaya University College of Medical Sciences,

nxiety, phobias and stress are the main mental health problems among the Malaysian population, with

global prevalence varying from 8% to 18%. Even so, less than 30% who suffer these disturbances seek

treatment. The objective of this study is to evaluate and compare the anxiolytic effects of

Aconitum napellus

and

Homeopathic complex Vita-C 15 in the acutely stressed C57BL6 mice by using the fecal corticoid test, open field

test (OFT) and c-fos, NMDAR 2B, NPY 1R and NPY 2R activity through the hippocampus. A double blinded

randomized controlled study is conducted at Animal Laboratory of Cyberjaya University College of Medical

Sciences (CUCMS). All the animals are acclimatized to constant laboratory conditions for 14 days before starting

the experiments. Prior to the experiment, a pilot study is performed to identify the most suitable and ideal potency

for the homeopathic remedy of

Aconitum napellus

. The animals are tested (n=3) per group on the potency of 6 C,

30 C and 200 C. The treatments are carried out over 9 days. 48 male C57BL6 mice (n=6), 4-5 weeks of age are

used. They are randomly selected and divided into two groups. Group I is the healthy control group of mice which

are not exposed to acute stress. Group II (stress group); comprise of mice expose to acute restraint stress. Prior to

restraint stress, the treatments given are

Aconitum napellus

30 cH, Homeopathic complex Vita-C 15, Diazepam,

and placebo. Then the results are evaluated by fecal CORT test and open field test by comparing the anxiolytics

between pre-test and post-test.

Aconitum napellus

30 cH and Homeopathic complex Vita-C 15 are expected to be

more effective and can reduce the occurrence of anxiety in the acutely stressed C57BL6 mice. Thus research into

prevention and supportive therapies is necessary and beneficial for this disorder.