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Volume 02
Clinical Pharmacology and Toxicology Research
Toxicology 2019
November 11-12, 2019
November 11-12, 2019 | London, UK
TOXICOLOGY AND CLINICAL TOXICOLOGY
2
nd
International Conference on
Clin Pharmacol Toxicol Res, Volume 02
The impact of Lambda cyhalothrin insecticide on the parameters and chemical
metabolites in the kidneys of Wistar rats
Guefaifia Yahia
University of Tebessa, Algeria
L
ambda cyhalothrin is a synthetic pyrethroid insecticide type II, with increasing agricultural uses. This active substance
consists of two of the four enantiomeric forms of cyhalothrin. This study was carried out on a group of rats (18 rats)
treated with LCT (05 mg / kg / day), group C (06 rats) treated with LCT (10 mg / kg / day) orally for 90 days This work is
for the evaluation of the potential toxicity of LCT on the kidneys of rats and the variation of certain biochemical parameters
and metabolites. The results obtained after administration of LCT show that it caused an increase in urea and creatinine also a
disturbance of the main macromolecules namely proteins, lipids in treated rats with this two doses compared to controls. All of
these variations are signs of the toxicity of this insecticide to the kidneys of Wistar rats.
Biography
Guefaifia Yahia completed his bachelor diploma in animal biology and physiology and his master diploma in animal Ecophysiology from
Tebessa University. He is now working as a pharmacist.
e
:
yahya.out12@gmail.com