Previous Page  17 / 18 Next Page
Information
Show Menu
Previous Page 17 / 18 Next Page
Page Background

Page 45

Notes:

Volume 2

Journal of Clinical Diagnosis and Treatment

Annual Nephrology & Chronic Diseases 2019

May 20-21, 2019

Nephrology

Chronic Diseases

May 20-21, 2019 London, UK

19

th

Annual Conference on

3

rd

International Conference on

&

Prognostic value of Montreal cognitive assessment in heart failure patients

Lyu Siqi

and

Yu Litian

Peking Union Medical College, China

Objective:

To explore the occurrence of cognitive impairment in Chinese heart failure (HF) patients and its

impact on prognosis.

Methods:

A total of 990 patients were enrolled from 24 hospitals in China during December 2012 to

November 2014. All patients were administrated with the interview-format MoCA, according to which

they were divided into MoCA

26 group and MoCA≥26 group. Baseline data were collected and a 1-year

follow-up was carried out. Univariate and multivariate Cox regression were performed for 1-year outcomes.

Results:

628 patients (63.4%) had cognitive impairment and they were more likely to be older, female,

less educated, uninsured and New York Heart Association class III-IV. Compared with MoCA≥26 group,

the rate of intervention, device implantation, cardiac surgery and evidence-based medications were

significantly lower in MoCA

26 group (all p

0.05). As to the 1-year outcomes, MoCA

26 group had

higher all-cause mortality (10.2% vs. 2.2%, p<0.001), cardiovascular mortality (5.9% vs. 0.8%, p<0.001) and

major cardiovascular events (MACE) (9.6% vs. 2.5%, p<0.001) than MoCA≥26 group. After adjustment

by multivariate regression, MoCA

26 was indicated as a significant risk factor for all-cause mortality

[HR(95

CI): 4.212(1.987-8.927), p<0.001], cardiovascular mortality [HR(95

CI): 7.632(2.316-25.147),

p=0.001] and MACE [OR(95

CI): 4.229(2.006-8.914), p<0.001], while not for hospitalization for HF.

Conclusion:

Cognitive impairment was common in HF patients and was identified as an independent

prognostic marker for 1-year outcomes. Routine cognitive function assessment and active intervention are

recommended for HF patients.

lvsiqi138@163.com

J Clinical Diagnosis and Treatment, Volume 2