stem-cells-2019-scientifictracks

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Volume 02

Stem Cells 2019 & Pediatrics Congress 2019

November 06-07, 2019

Journal of Clinical Genetics and Genomics

November 06-07, 2019 | Tokyo, Japan

STEM CELLS AND REGENERATIVE MEDICINE

PEDIATRICS AND CHILD CARE

International Conference on

World Congress on

J Clin Gen Genomics, Volume 02

Nanohydroxyapatite coatings doped with nanocopper particles on Ti13Zr13Nb

titanium alloy for biomedical application

Michal Bartmanski

Gdansk University of Technology, Poland

Introduction

: Nowadays, the most commonly used titanium alloys for long-term implants are Ti6Al4V and less Ti6Al7Nb.

The negative effect of Al (may cause Alzheimer’s disease and softens bone process) and V (may provoke cytological responses

and damage neurological disorders in the nervous system) was reported. To ensure proper connection between human bone

and implants surface, improve biocompatibility and mechanical properties, many types of surface modifications were used,

such as the calcium phosphate-based coatings (e.g., hydroxyapatite), laser treatment, anodization and etching. Unfortunately,

these modifications do not fully meet the requirements set for them; hydroxyapatite coatings are usually thick and with poor

mechanical properties, which may damage the coating during the implantation process preventing primary stabilization.

Methodology

: In presented research the new generation Ti13Zr13Nb alloy, without toxic elements and with mechanical

properties (~E = 79 GPa) closer than Ti6Al4V (~E = 110 GPa) to the human bone (~E = 10-30 GPa) were proposed. The

nanohydroxyapatite coatings with nanocopper particles were deposited using the electrophoretic method in a one-way process.

To study properties of obtained coatings, the scanning electron microscopy, atomic force microscopy, energy-dispersive X-ray

spectroscopy, nanoindentation and nanoscratch-test techniques were used.

Results

: The study confirmed that it is possible to obtain homogenous

nanohydroxyapatite coatings with nanocopper particles in a way

electrophoretic deposition process. The positive effect of presents nanocopper

in coatings on thickness, topography and nanomechanical properties was

obtained.

Future plans

: Based on the positive results of preliminary tests, the authors

plan to perform tests on the rate of release of nanocopper particles into SBF

solutions as well as cytotoxicity and bactericidal properties tests.

Biography

Michal Bartmanski has his expertise in biomaterials and nanobiomaterials engineering, surface engineering and nanotechnology. The

main achievements include deposit of nanohydroxyapatite coatings, nanoHAp coatings with nanometals with bactericidal properties

and smart coatings on titanium alloys for biomedical applications and characteristic their mechanical (e.g., nanoindentation technique),

chemical (e.g. release of elements to simulated body fluids), physical (e.g. surface topography) and biological (e.g. cytotoxicity)

properties. Research-based on new modifications of biomaterials surface will allow in the future to develop more biocompatibility long-

term implants.